A first-in-human dose-escalation study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of oral 2-hydroxyoleic acid (2-OHOA) in adult patients (pt) with advanced solid tumors including grade III/IV glioblastoma multiforme (GBM).

Authors

null

Desamparados Roda

The Institute of Cancer Research and The Royal Marsden, London, United Kingdom

Desamparados Roda , Yvette Drew , Analia Azaro , Alan David Smith , Alastair Greystoke , Elisabet Sicart , Pablo V. Escriba , Xavier Busquets , Victoria LLado , Vicente Tur , Edwin Klumper , Jordi Rodon Ahnert , L Rhoda Molife , Ruth Plummer

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Poster Details

Meeting

2015 ASCO Annual Meeting

Session Type

Poster Discussion Session

Session Title

Developmental Therapeutics—Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics and Translational Research

Sub Track

Cytotoxic and Other Novel Agents

Clinical Trial Registration Number

NCT01792310

Citation

J Clin Oncol 33, 2015 (suppl; abstr 2513)

DOI

10.1200/jco.2015.33.15_suppl.2513

Abstract #

2513

Poster Bd #

229

Abstract Disclosures