A dose escalation, single arm, phase Ib-II combination study of BEZ235 with everolimus to determine the safety, pharmacodynamics and pharmacokinetics in subjects with advanced solid malignancies including glioblastoma multiforme.

Authors

null

Mohamad Adham Salkeni

University of Cincinnati Cancer Institute, Cincinnati, OH

Mohamad Adham Salkeni , Muhammad Shaalan Beg , Olugbenga Olanrele Olowokure , Hassana Fathallah , Hala Thomas , Carol A Mercer , Mahmoud Charif , Rekha T. Chaudhary , Nagla Abdel Karim , Ronald Warnick , Christopher McPherson , Ganesh Moorthy , Pankaj B Desai , Sara Kozma , George Thomas , Olivier Rixe

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Poster Details

Meeting

2012 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics - Experimental Therapeutics

Track

Developmental Therapeutics

Sub Track

PI3-Akt-mTOR Pathway

Clinical Trial Registration Number

NCT01508104

Citation

J Clin Oncol 30, 2012 (suppl; abstr TPS3116)

DOI

10.1200/jco.2012.30.15_suppl.tps3116

Abstract #

TPS3116

Poster Bd #

22B

Abstract Disclosures

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