Safety, pharmacokinetics, and clinical activity of OBI-3424, an AKR1C3‑activated prodrug, in patients with advanced or metastatic solid tumors: A phase 1 dose-escalation study.

Authors

Apostolia Tsimberidou

Apostolia Maria Tsimberidou

Department of Investigational Cancer Therapeutics, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX

Apostolia Maria Tsimberidou , Claire F. Verschraegen , Pei Hsu , Tillman E. Pearce

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Poster Details

Meeting

2022 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

Track

Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

Sub Track

Chemotherapy and Antibody-Drug Conjugates

Clinical Trial Registration Number

NCT03592264

Citation

J Clin Oncol 40, 2022 (suppl 16; abstr 3030)

DOI

10.1200/JCO.2022.40.16_suppl.3030

Abstract #

3030

Poster Bd #

22

Abstract Disclosures