A phase 1 dose-escalation study to investigate the safety, efficacy, pharmacokinetics, and pharmacodynamic activity of cln-619 (Anti-MICA/B antibody) alone and in combination with pembrolizumab in patients with advanced solid tumors.

Authors

Judy Wang

Judy S. Wang

Sarah Cannon Research Institute at Florida Cancer Specialists, Sarasota, FL

Judy S. Wang , Martin Gutierrez , Drew W. Rasco , Ignacio Melero Bermejo , John D. Powderly , Erika P. Hamilton , Michael Millward , Ana Maria Arance , Rafal Stec , Victor Moreno , Manish Sharma , Iwona A. Lugowska , Mark J. Shackleton , Sophia Frentzas , John Edward Janik , Tracy Liu , Irina Shapiro , Kerry Whalen , Jeffrey Alan Jones , Alexander I. Spira

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Poster Details

Meeting

2023 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics—Immunotherapy

Track

Developmental Therapeutics—Immunotherapy

Sub Track

Antibodies

Clinical Trial Registration Number

NCT05117476

Citation

J Clin Oncol 41, 2023 (suppl 16; abstr 2532)

DOI

10.1200/JCO.2023.41.16_suppl.2532

Abstract #

2532

Poster Bd #

374

Abstract Disclosures