First-in-human phase 1 trial (DRAGON) of SRK-181, a potential first-in-class selective latent TGFβ1 inhibitor, alone or in combination with anti-PD-(L)1 treatment in patients with advanced solid tumors.

Authors

Timothy Yap

Timothy A. Yap

The University of Texas MD Anderson Cancer Center, Houston, TX

Timothy A. Yap , Minal A. Barve , Justin F. Gainor , Colin D. Weekes , Bruno Bockorny , Yawen Ju , Ryan Faucette , Sanela Bilic , Si Tuen Lee-Hoeflich , Guochen Song , Yung Chyung , Michelle Legler , Lu Gan , Johanna C. Bendell

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Poster Details

Meeting

2021 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

Track

Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

Sub Track

New Targets and New Technologies (non-IO)

Clinical Trial Registration Number

NCT04291079

Citation

J Clin Oncol 39, 2021 (suppl 15; abstr TPS3146)

DOI

10.1200/JCO.2021.39.15_suppl.TPS3146

Abstract #

TPS3146

Poster Bd #

Online Only

Abstract Disclosures