A phase Ib study of prexasertib, a checkpoint kinase (CHK1) inhibitor, and LY3023414, a dual inhibitor of class I phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR) in patients with advanced solid tumors.

Authors

David S. Hong

David S. Hong

The University of Texas MD Anderson Cancer Center, Houston, TX

David S. Hong , Kathleen N. Moore , Johanna C. Bendell , Daniel D. Karp , Judy Sing-Zan Wang , Susanna Varkey Ulahannan , Melissa Lynne Johnson , Raid Aljumaily , Scott Hynes , Sophie Callies , Rodney Decker , Elizabeth LaBell , Michele Niland , Xuejing Aimee Wang , Aimee Bence Lin , Manish R. Patel

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Poster Details

Meeting

2019 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics and Tumor Biology (Nonimmuno)

Track

Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

Sub Track

New Targets and New Technologies (non-IO)

Clinical Trial Registration Number

NCT02124148

Citation

J Clin Oncol 37, 2019 (suppl; abstr 3091)

DOI

10.1200/JCO.2019.37.15_suppl.3091

Abstract #

3091

Poster Bd #

83

Abstract Disclosures

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