A phase IB study of the combination of selumetinib (AZD6244, ARRY-142886) and cyclosporin A (CsA) in patients with advanced solid tumors with an expansion cohort in metastatic colorectal cancer (mCRC).

Authors

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Anuradha Krishnamurthy

University of Colorado-Denver, Aurora, CO

Anuradha Krishnamurthy , A. Dasari , Anne M. Noonan , Janice M. Mehnert , Albert C. Lockhart , Mark N. Stein , Hanna Kelly Sanoff , James J. Lee , Aaron Richard Hansen , Usha Malhotra , Sarah Rippke , Sarah Lindsey Davis , Wells A. Messersmith , S. Gail Eckhardt , Christopher Hanyoung Lieu

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Poster Details

Meeting

2017 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics—Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics and Translational Research

Sub Track

Small Molecules

Clinical Trial Registration Number

NCT02188264

Citation

J Clin Oncol 35, 2017 (suppl; abstr 2587)

DOI

10.1200/JCO.2017.35.15_suppl.2587

Abstract #

2587

Poster Bd #

79

Abstract Disclosures