Combination of a MEK inhibitor, pimasertib (MSC1936369B), and a PI3K/mTOR inhibitor, SAR245409, in patients with advanced solid tumors: Results of a phase Ib dose-escalation trial.

Authors

null

Rebecca Suk Heist

Massachusetts General Hospital, Boston, MA

Rebecca Suk Heist , Leena Gandhi , Geoffrey Shapiro , Naiyer A. Rizvi , Howard A. Burris III, Johanna C. Bendell , Jose Baselga , Scott B Yerganian , Karl Hsu , Janet Ogden , Loïc Vincent , Oliver von Richter , Giuseppe Locatelli , Ekatherine Asatiani , Jeffrey R. Infante

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Poster Details

Meeting

2013 ASCO Annual Meeting

Session Type

Poster Discussion Session

Session Title

Developmental Therapeutics - Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics

Sub Track

PI3-Akt-mTOR Pathway

Clinical Trial Registration Number

NCT01390818

Citation

J Clin Oncol 31, 2013 (suppl; abstr 2530)

DOI

10.1200/jco.2013.31.15_suppl.2530

Abstract #

2530

Poster Bd #

18

Abstract Disclosures

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