Phase 1 study of the p53-MDM2 inhibitor AMG 232 combined with trametinib plus dabrafenib or trametinib in patients (Pts) with TP53 wild type (TP53WT) metastatic cutaneous melanoma (MCM).

Authors

Stergios Moschos

Stergios J. Moschos

University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC

Stergios J. Moschos , Shahneen Kaur Sandhu , Karl D. Lewis , Ryan J. Sullivan , Douglas Buckner Johnson , Yilong Zhang , Erik Rasmussen , Haby A. Henary , Georgina V. Long

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Poster Details

Meeting

2017 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics—Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics and Translational Research

Sub Track

Small Molecules

Clinical Trial Registration Number

NCT02110355

Citation

J Clin Oncol 35, 2017 (suppl; abstr 2575)

DOI

10.1200/JCO.2017.35.15_suppl.2575

Abstract #

2575

Poster Bd #

67

Abstract Disclosures

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