A phase 1, dose-escalation, safety, pharmacokinetic, pharmacodynamic study of thioureidobutyronitrile, a novel p53 targeted therapy, in patients with advanced solid tumors.

Authors

null

Geoffrey Shapiro

Dana-Farber Cancer Institute, Boston, MA

Geoffrey Shapiro , James Walter Mier , John Frederick Hilton , Leena Gandhi , Nicole G. Chau , Andrea J. Bullock , Jeffrey G Supko , Sigitas Jonas Verselis , Kayla Murgo , Cameron Sze , Susan Gotthardt , Andrew Wolanski , W. James Alexander , Ashok Kumar , Sylvia Adell Holden , Karima Chafai-Fadela , Siya Ram , Krishna E. Menon

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Poster Details

Meeting

2015 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics—Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics and Translational Research

Sub Track

Cytotoxic and Other Novel Agents

Clinical Trial Registration Number

NCT01664000

Citation

J Clin Oncol 33, 2015 (suppl; abstr TPS2613)

DOI

10.1200/jco.2015.33.15_suppl.tps2613

Abstract #

TPS2613

Poster Bd #

323a

Abstract Disclosures

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