A phase I, dose-escalation, safety, pharmacokinetic, pharmacodynamic study of thioureidobutyronitrile, a novel p53 targeted therapy, in patients with advanced solid tumors.

Authors

null

Geoffrey Shapiro

Dana-Farber Cancer Institute, Boston, MA

Geoffrey Shapiro , Jeffrey G Supko , Daniel C. Cho , John Frederick Hilton , Matthew Hadfield , Solida Pruitt-Thompson , Eveline Bordoli-Trachsela , Nela Zvereva , Andrew Wolanski , Aya Sato-DiLorenzo , Susan Gotthardt , Edward A. Fox , Sigitas Jonas Verselis , Ashok Kumar , Sylvia A. Holden , Siya Ram , Karima Chafai-Fadela , Kimberly Harding , Krishna E. Menon

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Poster Details

Meeting

2013 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics - Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics

Sub Track

Signal Transduction

Clinical Trial Registration Number

NCT01664000

Citation

J Clin Oncol 31, 2013 (suppl; abstr TPS2627)

DOI

10.1200/jco.2013.31.15_suppl.tps2627

Abstract #

TPS2627

Poster Bd #

12G

Abstract Disclosures

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