A first-in-human (FIH) dose-escalation study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of intravenous BAL101553, a novel microtubule inhibitor, in adult patients with advanced solid tumors.

Authors

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Alan Hilary Calvert

University College London, London, United Kingdom

Alan Hilary Calvert , Michael Gonzalez , Sushila Ganguli , Matthew Ng , Sarah Benafif , Marta Capelan , Robert Goldstein , Krunal Shah , Claire Jarvis , Michael Flynn , Martin Forster , Stephanie Anderson , Anne Schmitt-Hoffman , Heidi Lane , Marc Engelhardt , Alison L. Hannah , Alexandar Tzankov , Felix Bachmann , L Rhoda Molife , Rebecca Kristeleit

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Poster Details

Meeting

2013 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics - Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics

Sub Track

Cytotoxic and Other Novel Agents

Clinical Trial Registration Number

NCT01397929

Citation

J Clin Oncol 31, 2013 (suppl; abstr 2566)

DOI

10.1200/jco.2013.31.15_suppl.2566

Abstract #

2566

Poster Bd #

5B

Abstract Disclosures