Guideline: Genitourinary Cancer

Clinically Localized Prostate Cancer

Guideline Status: Current

Published Online: September 5, 2018

Last Updated: March 21, 2023

Published online ahead of print September 5, 2018, doi: 10.1200/JCO.18.00606

Justin E. Bekelman, R. Bryan Rumble, Ronald C. Chen, Thomas M. Pisansky, Antonio Finelli, Andrew Feifer, Paul L. Nguyen, D. Andrew Loblaw, Scott T. Tagawa, Silke Gillessen, Todd M.Morgan, Glenn Liu, Neha Vapiwala, John J. Haluschak, Andrew Stephenson, Karim Touijer, Terry Kungel, and Stephen J. Freedland

Purpose

In April 2017, the American Urological Association, American Society for Radiation Oncology, and Society of Urologic Oncology released a joint evidence-based practice guideline on clinically localized prostate cancer. The American Society of Clinical Oncology (ASCO) has a policy and set of procedures for endorsing clinical practice guidelines that have been developed by other professional organizations.

Methods

The Clinically Localized Prostate Cancer guideline was reviewed for developmental rigor by methodologists. An ASCO Expert Panel then reviewed the content and the recommendations.

Results

The ASCO Expert Panel determined that the recommendations from the Clinically Localized Prostate Cancer guideline were clear, thorough, and based upon the most relevant scientific evidence. ASCO endorsed the Clinically Localized Prostate Cancer guideline except for two recommendations on cryosurgery. The two recommendations covering cryosurgery were not endorsed because the panel found that there is insufficient evidence to support the use of cryotherapy in this setting.

Recommendations

The ASCO Expert Panel endorsed all but two of the original guideline recommendations as written and offered a series of discussion points to guide practice.

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