Radiation Therapy for Small Cell Lung Cancer
Guideline Status: Current
Published Online: January 27, 2021
Last Updated: March 21, 2023
Published ahead of print January 27, 2021, DOI: 10.1200/JCO.20.03364
Megan E. Daly, MD; Nofisat Ismaila, MD; Roy H. Decker, MD, PhD; Kristin Higgins, MD; Dawn Owen, MD, PhD; Ashish Saxena, MD, PhD; Gregg E. Franklin, MD, PhD; Dusty Donaldson, MA; and Bryan J. Schneider, MD
Purpose
The American Society for Radiation Oncology (ASTRO) produced an evidence-based guideline on radiation therapy (RT) for small-cell lung cancer (SCLC). Because of the relevance of this topic to ASCO membership, ASCO reviewed the guideline, applying a set of procedures and policies used to critically examine guidelines developed by other organizations.
Methods
The ASTRO guideline on RT for SCLC was reviewed for developmental rigor by methodologists. Then, an ASCO Expert Panel reviewed the content and the recommendations.
Results
The ASCO Expert Panel determined that the recommendations from ASTRO guideline on RT for SCLC, published in June 2020, are clear, thorough, and based upon the most relevant scientific evidence. ASCO endorsed ASTRO guideline on RT for SCLC with a few discussion points.
Recommendations
Recommendations addressed thoracic radiotherapy for limited-stage SCLC, role of stereotactic body radiotherapy in stage I or II node-negative SCLC, prophylactic cranial radiotherapy, and thoracic consolidation for extensive-stage SCLC.
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