Centre Pluridisciplinaire d'Oncologie, Lausanne, Switzerland
Serge Leyvraz , Stefan Suciu , Sophie Piperno-Neumann , Jean-Francois Baurain , Marcin Zdzienicki , Alessandro Testori , Ernest Marshall , Max E. Scheulen , Thomas Jouary , Sylvie Negrier , Jan Baptist Vermorken , Eckhart Kaempgen , Xavier Durando , Dirk Schadendorf , Ravichandra Karra Gurunath , Larissa Polders , Gaetan De Schaetzen , Simon Vanderschaeghe , Marie-Pierre Gauthier , Ulrich Keilholz
All pts (N=171) |
Treatment started (N=149) |
|||
---|---|---|---|---|
Endpoint | HIA (N=86) | IV (N=85) | HIA (N=66) | IV (N=83) |
Response | ||||
CR+PR=ORR, N (%) | 9 (10.5) | 2 (2.4) | 9 (13.6) | 2 (2.4) |
PFS | ||||
Events, N | 84 | 85 | 64 | 83 |
Median (months) | 4.5 | 3.7 | 5.4 | 3.7 |
HR (95% CI), p value | 0.62 (0.45 , 0.84), 0.002 | 0.53 (0.38 , 0.75), 0.0002 | ||
OS | ||||
Deaths, N | 79 | 76 | 59 | 74 |
Median (months) | 14.6 | 13.0 | 14.6 | 13.7 |
HR (95% CI), p value | 1.09 (0.79 , 1.50), 0.59 | 1.00 (0.71 , 1.42), 0.98 |
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Abstract Disclosures
2022 ASCO Annual Meeting
First Author: Roger Olofsson Bagge
2023 ASCO Annual Meeting
First Author: Roger Olofsson Bagge
2023 ASCO Annual Meeting
First Author: Sophie Piperno-Neumann
2024 ASCO Genitourinary Cancers Symposium
First Author: Miguel Muniz