Safety and efficacy results from two randomized expansions of a phase I study of a tablet formulation of the PARP inhibitor, olaparib, in ovarian and breast cancer patients with BRCA1/2 mutations.

Authors

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L Rhoda Molife

Royal Marsden Hospital and Institute of Cancer Research, Surrey, United Kingdom

L Rhoda Molife , Joaquin Mateo , Trevor McGoldrick , Matthew Krebs , Yvette Drew , Susana N. Banerjee , Shibani Nicum , Malcolm Ranson , Gordon J. S. Rustin , Cristiana Sessa , Ruth Plummer , Karin Leunen , Michael Friedlander , Helen Swaisland , Wendy Burke , Peter McCormack , Kristine Pemberton , Ilian Tchakov , Stanley B. Kaye , Charlie Gourley

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Poster Details

Meeting

2012 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics - Experimental Therapeutics

Track

Developmental Therapeutics

Sub Track

DNA Repair and Apoptosis

Clinical Trial Registration Number

NCT00777582

Citation

J Clin Oncol 30, 2012 (suppl; abstr 3048)

DOI

10.1200/jco.2012.30.15_suppl.3048

Abstract #

3048

Poster Bd #

13F

Abstract Disclosures

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