A first-in-human phase 1, multicenter, open-label study of CB-012, a next-generation CRISPR-edited allogeneic anti-CLL-1 CAR-T cell therapy for adults with relapsed/refractory acute myeloid leukemia (AMpLify).

Authors

null

Naval Guastad Daver

The University of Texas MD Anderson Cancer Institute, Houston, TX

Naval Guastad Daver , Abhishek Maiti , David Andrew Sallman , Gail J. Roboz , Melhem M. Solh , Filippo Milano , Stephen Anthony Strickland , Alireza Eghtedar , Steven Brian Kanner , Guy Ledergor , Donna Marcy , Elizabeth Garner , Brian J. Francica , McKay Shaw , Kalin Bird , Jennifer Rattan , Enrique Zudaire , Socorro Portella , Pankit Vachhani , Jae H. Park

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Poster Details

Meeting

2024 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant

Track

Hematologic Malignancies

Sub Track

Acute Leukemia

Clinical Trial Registration Number

NCT06128044

Citation

J Clin Oncol 42, 2024 (suppl 16; abstr TPS6586)

DOI

10.1200/JCO.2024.42.16_suppl.TPS6586

Abstract #

TPS6586

Poster Bd #

144b

Abstract Disclosures