Final overall survival results from phase 3 SPOTLIGHT study evaluating zolbetuximab + mFOLFOX6 as first-line (1L) treatment for patients (pts) with claudin 18 isoform 2 (CLDN18.2)+, HER2−, locally advanced (LA) unresectable or metastatic gastric or gastroesophageal junction (mG/GEJ) adenocarcinoma.

Authors

Kohei Shitara

Kohei Shitara

National Cancer Center Hospital East, Kashiwa, Japan

Kohei Shitara , Eric Van Cutsem , Florian Lordick , Peter C. Enzinger , David H. Ilson , Manish A. Shah , Rui-Hua Xu , Sara Lonardi , Kensei Yamaguchi , Yi-Ping Hung , Bozena Kukielka-Budny , Pranob P. Bhattacharya , Maria Matsangou , Ran Li , Diarmuid Martin Moran , Radhika Ranganath , Rupesh Pophale , Jaffer A. Ajani

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Poster Details

Meeting

2024 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary

Track

Gastrointestinal Cancer—Gastroesophageal, Pancreatic, and Hepatobiliary

Sub Track

Esophageal or Gastric Cancer - Advanced/Metastatic Disease

Clinical Trial Registration Number

NCT03504397

Citation

J Clin Oncol 42, 2024 (suppl 16; abstr 4036)

DOI

10.1200/JCO.2024.42.16_suppl.4036

Abstract #

4036

Poster Bd #

16

Abstract Disclosures