FusionVAC22_01: A phase I clinical trial evaluating a DNAJB1-PRKACA fusion transcript-based peptide vaccine combined with immune checkpoint inhibition for fibrolamellar hepatocellular carcinoma and other tumor entities carrying the oncogenic driver fusion.

Authors

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Michael Bitzer

Department for Internal Medicine I, Center for Personalized Medicine; Cluster of Excellence iFIT (EXC2180), Eberhard-Karls University, Tübingen, Germany

Michael Bitzer , Christopher Hackenbruch , Jens Bauer , Jonas S. Heitmann , Yacine Maringer , Annika Nelde , Helmut R. Salih , Juliane S. Walz

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Poster Details

Meeting

2024 ASCO Gastrointestinal Cancers Symposium

Session Type

Trials in Progress Poster Session

Session Title

Trials in Progress Poster Session B: Cancers of the Pancreas, Small Bowel, and Hepatobiliary Tract

Track

Pancreatic Cancer,Hepatobiliary Cancer,Neuroendocrine/Carcinoid,Small Bowel Cancer

Sub Track

Therapeutics

Clinical Trial Registration Number

NCT05937295

Citation

J Clin Oncol 42, 2024 (suppl 3; abstr TPS580)

DOI

10.1200/JCO.2024.42.3_suppl.TPS580

Abstract #

TPS580

Poster Bd #

P9

Abstract Disclosures

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