Gene expression signatures, stromal tumor infiltrating lymphocytes (sTILs), and change in tumor cellularity to predict pathological complete response (pCR) after 12 week de-escalated neoadjuvant endocrine therapy (ET) vs paclitaxel + dual HER2 blockade in the WSG-TP-II trial.

Authors

Monika Graeser

Monika Karla Graeser

West German Study Group, Moenchengladbach, Germany

Monika Karla Graeser , Oleg Gluz , Ulrike Nitz , Claudia Biehl , Angela Berg , Matthias Christgen , Sherko Kuemmel , Johannes Holtschmidt , Johannes Schumacher , Andreas D. Hartkopf , Jochem Potenberg , Kerstin Luedtke-Heckenkamp , Marianne Just , Christian Schem , Christine zu Eulenburg , Timo Schinkoethe , Rachel Wuerstlein , Ronald E. Kates , Hans Heinrich Kreipe , Nadia Harbeck

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Poster Details

Meeting

2023 ASCO Annual Meeting

Session Type

Poster Discussion Session

Session Title

Breast Cancer—Local/Regional/Adjuvant

Track

Breast Cancer

Sub Track

Neoadjuvant Therapy

Clinical Trial Registration Number

NCT03272477

Citation

J Clin Oncol 41, 2023 (suppl 16; abstr 519)

DOI

10.1200/JCO.2023.41.16_suppl.519

Abstract #

519

Poster Bd #

349

Abstract Disclosures