A phase 1, first-in-human, open label, escalation and expansion study of ORM-5029, a highly potent GSPT1 degrader targeting HER2, in patients with HER2-expressing advanced solid tumors.

Authors

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Sara A. Hurvitz

Division of Hematology/Oncology, David Geffen School of Medicine at the University of California Los Angeles/Jonsson Comprehensive Cancer Center, Los Angeles, CA

Sara A. Hurvitz , Erika P. Hamilton , Alexander I. Spira , Paula R Pohlmann , Antonio Giordano , Katherine Clifton , Barry Douglas Anderson , Sujoy Dutta , Umesh Mangipudi , Shikha Saini , James Palacino , Tina Karunaratne , Dennise Greensmith , Olaf Christensen , Sharon Wilks

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Poster Details

Meeting

2023 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Breast Cancer—Metastatic

Track

Breast Cancer

Sub Track

HER2-Positive

Clinical Trial Registration Number

NCT05511844

Citation

J Clin Oncol 41, 2023 (suppl 16; abstr TPS1114)

DOI

10.1200/JCO.2023.41.16_suppl.TPS1114

Abstract #

TPS1114

Poster Bd #

333b

Abstract Disclosures