A phase 1, open-label, dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of PF-07799933 (ARRY-440) as a single agent and in combination therapy in participants 16 years and older with advanced solid tumors with BRAF alterations.

Authors

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J. Thaddeus Thaddeus Beck

Highlands Oncology Group, Springdale, AR

J. Thaddeus Thaddeus Beck , Meredith McKean , Shirish M. Gadgeel , Daniel W. Bowles , Rizwan Haq , Rona Yaeger , Matthew H. Taylor , Arnab K. Maity , Stefanie Drescher , Colleen Oliver , Ann Marie Huelskamp , Gang Feng , Keren Sturtz

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Poster Details

Meeting

2023 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

Track

Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

Sub Track

Small Molecules

Clinical Trial Registration Number

NCT05355701

Citation

J Clin Oncol 41, 2023 (suppl 16; abstr TPS3164)

DOI

10.1200/JCO.2023.41.16_suppl.TPS3164

Abstract #

TPS3164

Poster Bd #

356b

Abstract Disclosures