First-in-human first-in-class phase 1/2a study of the next generation CDK4-selective inhibitor PF-07220060 in patients (pts) with advanced solid tumors, enriched for HR+ HER2- mBC who progressed on prior CDK4/6 inhibitors and endocrine therapy.

Authors

Timothy Yap

Timothy A. Yap

Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX

Timothy A. Yap , Antonio Giordano , Erika P. Hamilton , Patricia LoRusso , Michelle Bowers , Cynthia Basu , Stephane Billotte , Maria Delioukina , Feng Liu , Jing Yang , Manish Sharma

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Poster Details

Meeting

2023 ASCO Annual Meeting

Session Type

Poster Discussion Session

Session Title

Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

Track

Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

Sub Track

Small Molecules

Clinical Trial Registration Number

NCT04557449

Citation

J Clin Oncol 41, 2023 (suppl 16; abstr 3009)

DOI

10.1200/JCO.2023.41.16_suppl.3009

Abstract #

3009

Poster Bd #

207

Abstract Disclosures