Impact of race and payor status on patterns of utilization of partial and radical nephrectomy in patients with localized renal cell carcinoma (RCC).

Authors

Regina Barragán Carrillo

Regina Barragan-Carrillo

Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubiran, Mexico City, Mexico

Regina Barragan-Carrillo , Kai Dallas , Abhishek Tripathi , Ameish Govindarajan , Zeynep Busra Zengin , Luis A Meza , Errol James Philip , Daniela V. Castro , Alexander Chehrazi-Raffle , Neal Chawla , Joann Hsu , Nazli Dizman , Karyn Eilber , Cristiane Decat Bergerot , Sumanta Monty Pal

Organizations

Instituto Nacional de Ciencias Medicas y Nutrición Salvador Zubiran, Mexico City, Mexico, City of Hope Comprehensive Cancer Center, Duarte, CA, University of California, San Francisco, San Francisco, CA, City of Hope, Duarte, CA, Yale University School of Medicine, New Haven, CT, Cedars-Sinai Medical Center, Los Angeles, CA, Centro de Câncer de Brasília, Brasília, OR, Brazil, Department of Medical Oncology & Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA

Research Funding

No funding received
None.

Background: Racial minorities experience intersecting forms of marginalization and suffer significant healthcare disparities. Prospective trials have shown similar outcomes with partial and radical nephrectomy among patients with localized RCC (Van Poppel et al Eur Urol 2011), and multiple studies suggest increasing use of the former technique (Breau et al Can J Urol 2020). We hypothesize that patients from minority groups, as well as those with non-private insurance, will have less access to this specialized procedure and therefore have a higher rate of radical nephrectomy. Methods: We utilized the California Office of Statewide Health Planning and Development (OSHPD) database that collects information from all inpatient admissions, emergency room visits and inpatient/outpatient procedures in the state. All patients undergoing nephrectomy (both partial and radical) were identified from Jan 1, 2012 to Dec 31, 2018 using CPT and ICD-9/10 codes to identify patients. Demographic data was collected with specific attention to race and payor status. Univariate and multivariate analyses were conducted to determine the association between demographic data and procedure type. Results: In total, 31,093 patients were identified; 57% were males, with a mean age of 58 years. Among these, 16,142 (51.9%), 8,645 (27.8%), 2,795 (9.0%), 2,032 (6.5%) and 1,479 (4.8%) were characterized as White, Hispanic, Asian, Black and other, respectively. Partial nephrectomy and radical nephrectomy were performed in 15,840 (50.9%) and 15,253 (49.1%) of patients. By race, partial nephrectomy was performed in 8,576 (53.1%), 4,107 (47.5%), 1,286 (46.0%), 1,124 (55.3%) and 747 (50.5%) of White, Hispanic, Asian, Black and other patients, respectively (p<0.001). Use of partial nephrectomy also differed among patients based on payor status, with rates of 6,800 (56.4%), 5,036 (43.9%), 1,817 (38.3%) and 2,187 (77.7%) among patients with private, Medicare, indigent coverage (e.g., MediCal or Medicaid) and other insurance, respectively (p<0.001). On multivariate analysis controlling for age, gender, comorbidities and frailty, race was independently associated with type of nephrectomy procedure. Conclusions: Our study confirms that race and payor status may have an influence on utilization of partial versus radical nephrectomy, with the highest rate of partial nephrectomies among Whites and patients with private insurance. Although there are multiple potential confounders (e.g., latency of diagnosis and resulting tumor size/complexity), it is possible that access to care may be an important driver of these disparities.

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Abstract Details

Meeting

2023 ASCO Genitourinary Cancers Symposium

Session Type

Poster Session

Session Title

Poster Session C: Renal Cell Cancer; Adrenal, Penile, Urethral and Testicular Cancers

Track

Renal Cell Cancer,Adrenal Cancer,Penile Cancer,Testicular Cancer,Urethral Cancer

Sub Track

Cancer Disparities

Citation

J Clin Oncol 41, 2023 (suppl 6; abstr 614)

DOI

10.1200/JCO.2023.41.6_suppl.614

Abstract #

614

Poster Bd #

E4

Abstract Disclosures

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