A phase 1/2 open-label study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of OTX-2002 as a single agent and in combination with standard of care in patients with hepatocellular carcinoma and other solid tumor types known for association with the MYC oncogene (MYCHELANGELO I).

Authors

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Ildefonso I Rodriguez-Rivera

NEXT Oncology, San Antonio, TX;

Ildefonso I Rodriguez-Rivera , Ting-Hui Wu , Rachel Ciotti , William Senapedis , Kaitlyn Sullivan , Jeff Z Gao , Sangeetha Palakurthi , Thomas McCauley , Yan Moore

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Poster Details

Meeting

2023 ASCO Gastrointestinal Cancers Symposium

Session Type

Trials in Progress Poster Session

Session Title

Trials in Progress Poster Session B: Cancers of the Pancreas, Small Bowel, and Hepatobiliary Tract

Track

Pancreatic Cancer,Hepatobiliary Cancer,Neuroendocrine/Carcinoid,Small Bowel Cancer

Sub Track

Therapeutics

Clinical Trial Registration Number

NCT05497453

Citation

J Clin Oncol 41, 2023 (suppl 4; abstr TPS627)

DOI

10.1200/JCO.2023.41.4_suppl.TPS627

Abstract #

TPS627

Poster Bd #

N16

Abstract Disclosures