Phase II study (daNIS-1) of the anti–TGF-β monoclonal antibody (mAb) NIS793 with and without the PD-1 inhibitor spartalizumab in combination with nab-paclitaxel/gemcitabine (NG) versus NG alone in patients (pts) with first-line metastatic pancreatic ductal adenocarcinoma (mPDAC).

Authors

null

Li-Yuan Bai

China Medical University Hospital, Taichung, Taiwan;

Li-Yuan Bai , Teresa Macarulla , Peter Grell , Cheng Ean Chee , Anuradha Krishnamurthy , Mark Ka Wong , Michael Michael , Michele Milella , Gerald Prager , Christoph Springfeld , Joelle Collignon , Jens Siveke , Armando Santoro , Chia-Chi Lin , Katriina Johanna Peltola , Geraldine Bostel , Dragana Jankovic , Maria-Athina Altzerinakou , Claire Fabre , Shivan Sivakumar

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Poster Details

Meeting

2023 ASCO Gastrointestinal Cancers Symposium

Session Type

Trials in Progress Poster Session

Session Title

Trials in Progress Poster Session B: Cancers of the Pancreas, Small Bowel, and Hepatobiliary Tract

Track

Pancreatic Cancer,Hepatobiliary Cancer,Neuroendocrine/Carcinoid,Small Bowel Cancer

Sub Track

Therapeutics

Clinical Trial Registration Number

NCT04390763

Citation

J Clin Oncol 41, 2023 (suppl 4; abstr TPS761)

DOI

10.1200/JCO.2023.41.4_suppl.TPS761

Abstract #

TPS761

Poster Bd #

P17

Abstract Disclosures