NRG-GI004/SWOG-S1610: Colorectal Cancer Metastatic dMMR Immuno-Therapy (COMMIT) study—A randomized phase III study of atezolizumab (atezo) monotherapy versus mFOLFOX6/bevacizumab/atezo in the first-line treatment of patients (pts) with deficient DNA mismatch repair (dMMR) or microsatellite instability high (MSI-H) metastatic colorectal cancer (mCRC).

Authors

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Michael J. Overman

NSABP/NRG Oncology and University of Texas MD Anderson Cancer Center, and SWOG, Houston, TX;

Michael J. Overman , Greg Yothers , Samuel A. Jacobs , Hanna Kelly Sanoff , Deirdre Jill Cohen , Katherine A Guthrie , Norah Lynn Henry , Patricia A. Ganz , Scott Kopetz , Peter C. Lucas , Charles David Blanke , Theodore S. Hong , Norman Wolmark , Howard S. Hochster , Thomas J. George , Caio Max Sao Pedro Rocha Lima

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Poster Details

Meeting

2023 ASCO Gastrointestinal Cancers Symposium

Session Type

Trials in Progress Poster Session

Session Title

Trials in Progress Poster Session C: Cancers of the Colon, Rectum, and Anus

Track

Colorectal Cancer,Anal Cancer

Sub Track

Therapeutics

Clinical Trial Registration Number

NCT05080673

Citation

J Clin Oncol 41, 2023 (suppl 4; abstr TPS258)

DOI

10.1200/JCO.2023.41.4_suppl.TPS258

Abstract #

TPS258

Poster Bd #

N20

Abstract Disclosures

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