A multi-arm, phase 2, open-label study to assess the efficacy of RXC004 as monotherapy and in combination with nivolumab in patients with ring finger protein 43 (RNF43) or R-spondin (RSPO) aberrated, metastatic, microsatellite stable colorectal cancer following standard treatments.

Authors

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Scott Kopetz

The University of Texas MD Anderson Cancer Center, Houston, TX

Scott Kopetz , Van K. Morris II, Bert O'Neil , John A. Bridgewater , Janet Graham , Eileen E. Parkes , Mark P. Saunders , Elspeth Asken , Louise Goodwin , Caroline Phillips , Jane Robertson , Craig Tilston , Simon Woodcock , Natalie Cook

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Poster Details

Meeting

2022 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Gastrointestinal Cancer—Colorectal and Anal

Track

Gastrointestinal Cancer—Colorectal and Anal

Sub Track

Colorectal Cancer–Advanced Disease

Clinical Trial Registration Number

NCT04907539

Citation

J Clin Oncol 40, 2022 (suppl 16; abstr TPS3637)

DOI

10.1200/JCO.2022.40.16_suppl.TPS3637

Abstract #

TPS3637

Poster Bd #

426b

Abstract Disclosures

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