A phase 1/2 trial to evaluate the safety and antitumor activity of tipifarnib and alpelisib for patients with PIK3CA-mutated/amplified and/or HRAS-overexpressing recurrent/metastatic head and neck squamous cell carcinoma.

Authors

Glenn Hanna

Glenn J. Hanna

Dana-Farber Cancer Institute, Boston, MA

Glenn J. Hanna , Cesar Augusto Perez , Alan Loh Ho , Maura L. Gillison , Douglas Adkins , Ashley Dayoub , Andrew Saunders , Mollie Leoni , Stephen Dale , Kun Nie , Alex Dmitrienko

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Poster Details

Meeting

2022 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Head and Neck Cancer

Track

Head and Neck Cancer

Sub Track

Advanced/Metastatic Disease

Clinical Trial Registration Number

NCT04809233

Citation

J Clin Oncol 40, 2022 (suppl 16; abstr TPS6104)

DOI

10.1200/JCO.2022.40.16_suppl.TPS6104

Abstract #

TPS6104

Poster Bd #

92a

Abstract Disclosures