NeoOPTIMIZE: An open-label, phase II trial and biomarker discovery platform to assess the efficacy of adaptive switching of modified FOLFIRINOX (mFFX) or gemcitabine/nab-paclitaxel (GA) as a neoadjuvant strategy for patients with resectable/borderline resectable and locally advanced unresectable pancreatic ductal adenocarcinoma (PDAC).

Authors

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Charles D. Lopez

Oregon Health & Science University, Portland, OR

Charles D. Lopez , Adel Kardosh , Emerson Yu-sheng Chen , Skye C. Mayo , Robert Eil , Patrick Joseph Worth , Erin W. Gilbert , Flavio G. Rocha , Nima Nabavizadeh , Aaron Grossberg , Alexander Guimaraes , Bryan Foster , Brian Brinkerhoff , Shaun Goodyear , Erin Taber , Dove Keith , Jonathan Robert Brody , Gordon B. Mills , Rosalie Sears , Brett C. Sheppard

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Poster Details

Meeting

2022 ASCO Gastrointestinal Cancers Symposium

Session Type

Trials in Progress Poster Session

Session Title

Trials in Progress Poster Session B: Cancers of the Pancreas, Small Bowel, and Hepatobiliary Tract

Track

Pancreatic Cancer,Hepatobiliary Cancer,Neuroendocrine/Carcinoid,Small Bowel Cancer

Sub Track

Therapeutics

Clinical Trial Registration Number

NCT04539808

DOI

10.1200/JCO.2022.40.4_suppl.TPS630

Abstract #

TPS630

Poster Bd #

Q6

Abstract Disclosures