A phase 1 dose escalation and cohort expansion study of the safety and efficacy of allogeneic CRISPR-Cas9–engineered T cells (CTX110) in patients (Pts) with relapsed or refractory (R/R) B-cell malignancies (CARBON).

Authors

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Joseph McGuirk

Department of Blood and Bone Marrow Transplant, The University of Kansas Medical Center, Kansas City, KS

Joseph McGuirk , Carlos R. Bachier , Michael Russell Bishop , P. Joy Ho , Hemant S. Murthy , Michael J. Dickinson , Joseph E. Maakaron , Charalambos Andreadis , Armin Ghobadi , Edmund K. Waller , Mark Daniel Benton , Susanna Suh , Huansheng Xu , Ewelina Morawa , Farrukh Tauseef Awan , Paul Shaughnessy , Constantine Si Lun Tam , Nicolaus Kroeger , Richard T. Maziarz

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Poster Details

Meeting

2021 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia

Track

Hematologic Malignancies

Sub Track

Non-Hodgkin Lymphoma

Clinical Trial Registration Number

NCT04035434

Citation

J Clin Oncol 39, 2021 (suppl 15; abstr TPS7570)

DOI

10.1200/JCO.2021.39.15_suppl.TPS7570

Abstract #

TPS7570

Poster Bd #

Online Only

Abstract Disclosures