First-in-human phase I/II trial of PRGN-2009 vaccine as monotherapy or with bintrafusp alfa in patients with recurrent/metastatic (R/M) human papillomavirus (HPV)-associated cancers (HPVC) and as neoadjuvant/induction therapy in locoregionally advanced (LA) HPV oropharyngeal (OP) and sinonasal (SN) squamous cell cancer (SCC).

Authors

Charalampos Floudas

Charalampos S. Floudas

Genitourinary Malignancies Branch, NCI, NIH, Bethesda, MD

Charalampos S. Floudas , Julius Strauss , Clint Allen , Nyall R London Jr., Renee Nicole Donahue , Caroline Jochems , Seth M. Steinberg , Lisa M. Cordes , Sheri McMahon , Jenn Marte , Houssein Abdul Sater , Jason Redman , Fatima Karzai , Marijo Bilusic , Ravi Amrit Madan , Douglas E Brough , Amy Lankford , Jeffrey Schlom , James L. Gulley

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Poster Details

Meeting

2021 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Head and Neck Cancer

Track

Head and Neck Cancer

Sub Track

Local-Regional Disease

Clinical Trial Registration Number

NCT04432597

Citation

J Clin Oncol 39, 2021 (suppl 15; abstr TPS6092)

DOI

10.1200/JCO.2021.39.15_suppl.TPS6092

Abstract #

TPS6092

Poster Bd #

Online Only

Abstract Disclosures