First-in-human study of TAS3681, an oral androgen receptor (AR) antagonist with AR and AR splice variant (AR-SV) downregulation activity, in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) refractory to abiraterone (ABI) and/or enzalutamide (ENZ) and chemotherapy (CT).

Authors

null

Johann S. De Bono

Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom

Johann S. De Bono , Natalie Cook , Evan Y. Yu , Primo "Lucky" N. Lara Jr., Judy S. Wang , Yoshihiko Yamasaki , Ikuo Yamamiya , Ping Gao , Elizabeth Martine Calleja , Dana E. Rathkopf

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Poster Details

Meeting

2021 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Genitourinary Cancer—Prostate, Testicular, and Penile

Track

Genitourinary Cancer—Prostate, Testicular, and Penile

Sub Track

Prostate Cancer– Advanced/Castrate-Resistant

Clinical Trial Registration Number

NCT02566772

Citation

J Clin Oncol 39, 2021 (suppl 15; abstr 5031)

DOI

10.1200/JCO.2021.39.15_suppl.5031

Abstract #

5031

Poster Bd #

Online Only

Abstract Disclosures

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