Racial and gender disparities in stage at diagnosis for bladder cancer: Results from the surveillance, epidemiology, and end results (SEER) program, 2007 to 2016.

Authors

null

Sachin Gupta

Reading Hospital, West Reading, PA

Sachin Gupta , Monika Joshi , Xingran Weng , Li Wang

Organizations

Reading Hospital, West Reading, PA, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, Penn State College of Medicine, Hershey, PA

Research Funding

No funding received
None

Background: Little is known about the patterns of racial and gender disparities in bladder cancer (BC). This study will use national large database to explore those disparities. Methods: Data from the National Cancer Institute’sSurveillance, Epidemiology, and End Results (SEER) Program for cancer registries was used. Patients > = 18 years diagnosed with BC in the years 2007-2016 were identified from SEER 18 database. We used the data year 2007 because that was the year when insurance status was first collected in SEER. Chi-square tests and multinomial logistic regression were used. Results: A total of 78,151 (females: 25.58%) patients were included, with 82.74% being non-Hispanic whites, 5.83% non-Hispanic blacks, 6.69 % Hispanics and 4.74% others. Distribution of stage 0 through stage IV at diagnosis was 51.97%, 23.21%, 12.11%, 4.10% and 8.61% respectively. Blacks (P < 0.0001) and females (P < 0.0001) were diagnosed at later stages as in Table. e.g., 14.54% of blacks were diagnosed at stage IV, compared to 7.97% of whites; and 11.03% of females at stage IV vs. 7.77% of males. Racial disparity exists for any given insurance status. Within every age group, gender disparity exists. For example, for those under 50 years of age, 12.81% of women vs. 8.16% of men were diagnosed at stage IV. After controlling for age, marital status and insurance type, both gender (P < 0.0001) and race (P < 0.0001) were statistically significant in predicting stage at diagnosis. Conclusions: Racial disparity in stage at BC diagnosis was strong, with blacks suffering most from the disparity. Females were more likely to be diagnosed at later stages, and this gender disparity exists in all age groups and was not due to women living longer. The existence of both racial and gender disparities in BC makes black women most vulnerable to late diagnosis than any other racial/gender group. Oncologists treating BC patients should be aware of the racial and gender disparity. More research needs to be done to help improve early access to health care amongst female and minority BC patients.

Stage at diagnosis differ by gender and race.

Stage at diagnosisGender
(P < 0.0001)
Race
(P < 0.0001)
MaleFemaleNon-Hispanic WhiteNon-Hispanic blackHispanicOther
Stage 052.97%49.06%53.13%40.70%50.51%47.64%
Stage I24.17%20.44%23.07%23.79%22.90%25.43%
Stage II11.34%14.36%11.96%14.96%11.09%12.78%
Stage III3.75%5.11%3.86%6.02%4.51%5.19%
Stage IV7.77%11.03%7.97%14.54%10.99%8.97%

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Abstract Details

Meeting

2020 ASCO Virtual Scientific Program

Session Type

Publication Only

Session Title

Publication Only: Genitourinary Cancer—Kidney and Bladder

Track

Genitourinary Cancer—Kidney and Bladder

Sub Track

Bladder Cancer

Citation

J Clin Oncol 38: 2020 (suppl; abstr e17032)

DOI

10.1200/JCO.2020.38.15_suppl.e17032

Abstract #

e17032

Abstract Disclosures

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