Phase II trial of the MEK 1/2 inhibitor selumetinib (AZD6244, ARRY-142886 Hydrogen Sulfate) in adults with neurofibromatosis type 1 (NF1) and inoperable plexiform neurofibromas (PN).

Authors

null

Geraldine Helen O'Sullivan Coyne

Developmental Therapeutics Clinic/Early Clinical Trials Development Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD

Geraldine Helen O'Sullivan Coyne , Andrea M. Gross , Eva Dombi , Cecilia Tibery , Amanda Carbonell , Naoko Takebe , Joanne Derdak , Dominique Pichard , Apurva K. Srivastava , William Herrick , Ralph E. Parchment , Staci Martin , Pamela Wolters , Patricia Whitcomb , Lawrence Rubinstein , James H. Doroshow , Alice P. Chen , Brigitte C. Widemann

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Poster Details

Meeting

2020 ASCO Virtual Scientific Program

Session Type

Poster Session

Session Title

Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

Track

Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

Sub Track

Small Molecules

Clinical Trial Registration Number

NCT02407405

Citation

J Clin Oncol 38: 2020 (suppl; abstr 3612)

DOI

10.1200/JCO.2020.38.15_suppl.3612

Abstract #

3612

Poster Bd #

342

Abstract Disclosures

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