A phase II randomized study of telaglenastat, a glutaminase (GLS) inhibitor, versus placebo, in combination with pembrolizumab (Pembro) and chemotherapy as first-line treatment for KEAP1/NRF2-mutated non-squamous metastatic non-small cell lung cancer (mNSCLC).

Authors

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Ferdinandos Skoulidis

The University of Texas MD Anderson Cancer Center, Houston, TX

Ferdinandos Skoulidis , Joel W. Neal , Wallace L. Akerley , Paul K. Paik , Thales Papagiannakopoulos , Karen L. Reckamp , Jonathan W. Riess , Yonchu Jenkins , Sacha Holland , Francesco Parlati , Yijing Shen , Sam H. Whiting , Naiyer A. Rizvi

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Poster Details

Meeting

2020 ASCO Virtual Scientific Program

Session Type

Poster Session

Session Title

Lung Cancer—Non-Small Cell Metastatic

Track

Lung Cancer

Sub Track

Metastatic Non–Small Cell Lung Cancer

Clinical Trial Registration Number

NCT04265534

Citation

J Clin Oncol 38: 2020 (suppl; abstr TPS9627)

DOI

10.1200/JCO.2020.38.15_suppl.TPS9627

Abstract #

TPS9627

Poster Bd #

393

Abstract Disclosures