Association of an RNA signature (RS) with emergence of ICOS hi CD4 T cells and efficacy outcomes for the ICOS agonist vopratelimab (vopra) and nivolumab (nivo) in patients (pts) on the ICONIC trial.

Authors

Timothy Yap

Timothy A Yap

The University of Texas MD Anderson Cancer Center, Houston, TX

Timothy A Yap, Justin F. Gainor, Howard A. Burris, Shivaani Kummar, Russell Kent Pachynski, Margaret K. Callahan, Patricia LoRusso, Scott S. Tykodi, Geoffrey Thomas Gibney, Gerald Steven Falchook, Osama E. Rahma, Tanguy Y. Seiwert, Kyriakos P. Papadopoulos, James Walter Mier, Yasmin Hashambhoy-Ramsay, Daniel Felitsky, David Y. Lee, Lara McGrath, Christopher Harvey, Ellen Hooper

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Poster Details

Meeting

2020 ASCO-SITC Clinical Immuno-Oncology Symposium

Session Type

Poster Session

Session Title

Poster Session A

Track

Breast and Gynecologic Cancers,Developmental Therapeutics,Genitourinary Cancer,Head and Neck Cancer,Lung Cancer,Melanoma/Skin Cancers,Gastrointestinal Cancer,Combination Studies,Implications for Patients and Society,Miscellaneous Cancers,Hematologic Malignancies

Sub Track

Biomarkers and Inflammatory Signatures

Clinical Trial Registration Number

NCT02904226

Citation

J Clin Oncol 38, 2020 (suppl 5; abstr 14)

Abstract #

14

Poster Bd #

B8

Abstract Disclosures

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