A phase II trial with safety lead-in to evaluate the addition of APX005M, a CD40 agonistic monoclonal antibody, to standard-of-care doxorubicin chemotherapy for the treatment of advanced soft tissue sarcoma.

Authors

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Matthew Ingham

Columbia University College of Physicans and Surgeons, New York, NY

Matthew Ingham, Shing Mirn Lee, Sahil Doshi, Susana Hernandez, Shahnaz V. Singh-Kandah, Zoe Singer, Ovidiu C. Trifan, Gary K. Schwartz

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Poster Details

Meeting

2020 ASCO-SITC Clinical Immuno-Oncology Symposium

Session Type

Trials in Progress Poster Session

Session Title

Trials in Progress Poster Session B

Track

Breast and Gynecologic Cancers,Developmental Therapeutics,Genitourinary Cancer,Head and Neck Cancer,Lung Cancer,Melanoma/Skin Cancers,Gastrointestinal Cancer,Combination Studies,Implications for Patients and Society,Miscellaneous Cancers,Hematologic Malignancies

Sub Track

Immune Checkpoints and Stimulatory Receptors

Clinical Trial Registration Number

NCT03719430

Citation

J Clin Oncol 38, 2020 (suppl 5; abstr TPS85)

Abstract #

TPS85

Poster Bd #

D8

Abstract Disclosures