Phase I trial of IACS-010759 (IACS), a potent, selective inhibitor of complex I of the mitochondrial electron transport chain, in patients (pts) with advanced solid tumors.

Authors

Timothy Yap

Timothy A Yap

The University of Texas MD Anderson Cancer Center, Houston, TX

Timothy A Yap , Jordi Rodon Ahnert , Sarina Anne Piha-Paul , Siqing Fu , Filip Janku , Daniel D. Karp , Aung Naing , Ecaterina Elena Ileana Dumbrava , Shubham Pant , Vivek Subbiah , Apostolia Maria Tsimberidou , David S. Hong , Kelsey Meagan Rose , Quanyun Xu , Christopher P. Vellano , Mikhila Mahendra , Philip Jones , Maria Emilia Di Francesco , Joseph R. Marszalek , Funda Meric-Bernstam

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Poster Details

Meeting

2019 ASCO Annual Meeting

Session Type

Poster Discussion Session

Session Title

Developmental Therapeutics and Tumor Biology (Nonimmuno)

Track

Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology

Sub Track

Small Molecules

Clinical Trial Registration Number

NCT03291938

Citation

J Clin Oncol 37, 2019 (suppl; abstr 3014)

DOI

10.1200/JCO.2019.37.15_suppl.3014

Abstract #

3014

Poster Bd #

6

Abstract Disclosures

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