A phase 1, open label, dose escalation study of MGD009, a humanized B7-H3 x CD3 DART protein, in combination with MGA012, an anti-PD-1 antibody, in patients with relapsed or refractory B7-H3-expressing tumors.

Authors

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Sadhna Shankar

MacroGenics, Inc., Rockville, MD

Sadhna Shankar , Alexander I. Spira , James Strauss , Liqin Liu , Ross La Motte-Mohs , Tony Wu , Syd Johnson , Ezio Bonvini , Paul A. Moore , Jon M. Wigginton , Jim Vasselli

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Poster Details

Meeting

2018 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics—Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics and Translational Research

Sub Track

Antibodies

Clinical Trial Registration Number

NCT03406949

Citation

J Clin Oncol 36, 2018 (suppl; abstr TPS2601)

DOI

10.1200/JCO.2018.36.15_suppl.TPS2601

Abstract #

TPS2601

Poster Bd #

424b

Abstract Disclosures