Preliminary results of a first-in-human, first-in-class phase I study of MTL-CEBPA, a small activating RNA (saRNA) targeting the transcription factor C/EBP-α in patients with advanced liver cancer.

Authors

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Debashis Sarker

King's College London, London, United Kingdom

Debashis Sarker , Elizabeth Ruth Plummer , Bristi Basu , Tim Meyer , Kai-Wen Huang , T.R. Jeffry Evans , Duncan Spalding , Yuk Ting Ma , Daniel H. Palmer , Cheng Ean Chee , Nagy A Habib

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Poster Details

Meeting

2018 ASCO Annual Meeting

Session Type

Poster Discussion Session

Session Title

Developmental Therapeutics—Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics and Translational Research

Sub Track

Other Novel Agents

Clinical Trial Registration Number

NCT02716012

Citation

J Clin Oncol 36, 2018 (suppl; abstr 2509)

DOI

10.1200/JCO.2018.36.15_suppl.2509

Abstract #

2509

Poster Bd #

335

Abstract Disclosures

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