A phase I trial of selective PI3K inhibitor taselisib (tas) plus palbociclib (palb) with and without endocrine therapy incorporating pharmacodynamic (PD) studies in patients (pts) with advanced cancers.

Authors

Joline Lim

Joline Si Jing Lim

Royal Marsden Hospital, Sutton, United Kingdom

Joline Si Jing Lim , Uzma Saddia Asghar , Nikolaos Diamantis , Sarah Emily Ward , Mona Parmar , Beth Purchase , Florence I. Raynaud , Karen E Swales , Sarah Hrebien , Emma Hall , Holly Tovey , Hannah Bye , Juanita Suzanne Lopez , Alison Joanne Turner , Johann S. De Bono , Udai Banerji , Timothy Anthony Yap , Nicholas C. Turner , Paula Proszek

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Poster Details

Meeting

2017 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics—Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics and Translational Research

Sub Track

Small Molecules

Clinical Trial Registration Number

NCT02389842

Citation

J Clin Oncol 35, 2017 (suppl; abstr 2573)

DOI

10.1200/JCO.2017.35.15_suppl.2573

Abstract #

2573

Poster Bd #

65

Abstract Disclosures