Effect of a novel IL-2 cytokine immune agonist (NKTR-214) on proliferating CD8+T cells and PD-1 expression on immune cells in the tumor microenvironment in patients with prior checkpoint therapy.

Authors

null

Chantale Bernatchez

The University of Texas MD Anderson Cancer Center, Houston, TX

Chantale Bernatchez , Cara L. Haymaker , Michael E. Hurwitz , Harriet M. Kluger , Michael T. Tetzlaff , Natalie Jackson , Ivan Gergel , Mary Ann Tagliaferri , Jonathan Zalevsky , Ute Hoch , Christie Fanton , Ernesto Iacucci , Sandra Aung , Michael Imperiale , Ej Liao , Salah E Bentebibel , Nizar M. Tannir , Patrick Hwu , Mario Sznol , Adi Diab

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Poster Details

Meeting

2017 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics—Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics and Translational Research

Sub Track

Immunoconjugates

Clinical Trial Registration Number

NCT02869295

Citation

J Clin Oncol 35, 2017 (suppl; abstr 2545)

DOI

10.1200/JCO.2017.35.15_suppl.2545

Abstract #

2545

Poster Bd #

37

Abstract Disclosures

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