SWOG S1221: A phase 1 dose escalation study co-targeting MAPK-dependent and MAPK-independent BRAF inhibitor resistance in BRAF mutant advanced solid tumors with dabrafenib, trametinib, and GSK2141795 (ClinicalTrials.gov NCT01902173).

Authors

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Alain Patrick Algazi

University of California, San Francisco Medical Center- Mt. Zion, San Francisco, CA

Alain Patrick Algazi , James Moon , Bartosz Chmielowski , Roger Lo , Kari Lynn Kendra , Christopher D. Lao , Karl D. Lewis , Rene Gonzalez , Kevin Kim , John E. Godwin , Brendan D. Curti , Megan Othus , Antoni Ribas

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Poster Details

Meeting

2017 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics—Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics and Translational Research

Sub Track

Small Molecules

Clinical Trial Registration Number

NCT01902173

Citation

J Clin Oncol 35, 2017 (suppl; abstr 2578)

DOI

10.1200/JCO.2017.35.15_suppl.2578

Abstract #

2578

Poster Bd #

70

Abstract Disclosures