A phase 1 study to evaluate the safety, pharmacokinetics, pharmacodynamics, immunogenicity, and antitumor activity of the OX40 agonist MEDI0562 in combination with tremelimumab or durvalumab in adult aubjects with advanced solid tumors.

Authors

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Brendan D. Curti

Providence Cancer Center and Earle A. Chiles Research Institute, Portland, OR

Brendan D. Curti , Todd Michael Bauer , Neeltje Steeghs , A. Craig Lockhart , Francis J. Giles , John D. Powderly II, Naiyer A. Rizvi , Jonathan Wade Goldman , Samir Khleif , Matthew Joseph Gribbin , Jennifer T. McDevitt , Scott A Hammond , Victoria L Chiou , Aurelien Marabelle

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Poster Details

Meeting

2017 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Developmental Therapeutics—Immunotherapy

Track

Developmental Therapeutics and Translational Research,Immunotherapy

Sub Track

Immune Checkpoint Inhibitors

Clinical Trial Registration Number

NCT02705482

Citation

J Clin Oncol 35, 2017 (suppl; abstr TPS3100)

DOI

10.1200/JCO.2017.35.15_suppl.TPS3100

Abstract #

TPS3100

Poster Bd #

190b

Abstract Disclosures