Dose escalation results of a phase 1b study of the MDM2 inhibitor AMG 232 with or without trametinib in patients (Pts) with relapsed/refractory (r/r) acute myeloid leukemia (AML).

Authors

Harry Erba

Harry Paul Erba

University of Alabama at Birmingham, Birmingham, AL

Harry Paul Erba , Pamela S. Becker , Paul J. Shami , Michael Richard Grunwald , Donna L. Flesher , Yilong Zhang , Erik Rasmussen , Haby A. Henary , Eunice S. Wang

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Poster Details

Meeting

2017 ASCO Annual Meeting

Session Type

Poster Session

Session Title

Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant

Track

Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant

Sub Track

Acute Leukemia

Clinical Trial Registration Number

NCT02016729

Citation

J Clin Oncol 35, 2017 (suppl; abstr 7027)

DOI

10.1200/JCO.2017.35.15_suppl.7027

Abstract #

7027

Poster Bd #

227

Abstract Disclosures

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