Tubular carcinoma of the breast: A single institution's experience of prognosis.

Authors

null

William P Boyan Jr.

Monmouth Medical Center, Long Branch, NJ

William P Boyan Jr., Michael Farr , Brian Shea , Manpreet Kohli , Ernest Ginalis

Organizations

Monmouth Medical Center, Long Branch, NJ

Research Funding

No funding sources reported

Background: Tubular carcinoma is a less aggressive form of breast cancer which emcompasses 1-4% of invasive breast cancer. Prior studies have shown a nearly 100% 15 year survival rate for tubular carcinoma compared to the 89.2% five year survival of all breast cancers. The question asked is if these two cancers should be treated the same. The goal of oncologic treatment is to maximize survival while limiting side effects. At the very least, care givers should be able to give prognostic encouragement to patients based on this less aggressive histological subtype. Methods: A retrospective study of charts for tubular carcinoma of the breast from 2000 to 2015 were analyzed. A total of 57 patients were captured. All relevant aspects of the patients history, as well as therapies rendered and outcomes were documented. The aim of our study was compare treatment outcomes in our group of tubular carcinomas to that of breast cancer as a whole. Results: A total of 57 patients were diagnosed and treated for tubular carcinoma of the breast between 2000 and 2015 from a single institution. Of the 57 patients, local recurrence was seen in two patients. The first patient underwent lumpectomy, endocrine and radiation therapy then recurred as an invasive ductal carcinoma 12 years later. A second patient underwent lumpectomy with endocrine treatment but refused radiation, recurring as a tubular carcinoma 10 months later. In our 16 year sample the recurrence rate was 3.5% or 1.75% recurring as tubular. This is lower than the rates of recurrence of all breast cancer. To this date there were no cancer related mortalities in our group. Conclusions: A look into our institution’s data supported the notion that tubular carcinoma of the breast is a less aggressive histological type. Of our 57 cases and mean follow up time of six years ranging from one year to fifteen, only two recurrences (3.5%) were noted and there was no cancer related mortalities. Interestingly only one (1.75%) recurred as tubular carcinoma. Without controlling for adjuvant therapy, recommendations cannot be made for a less aggressive treatment plan at this point. Based on this study and others like it physicians can give evidenced based favorable prognosis when the diagnosis of tubular carcinoma is made.

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Abstract Details

Meeting

2015 Breast Cancer Symposium

Session Type

Poster Session

Session Title

Poster Session A: Risk Assessment, Prevention, Early Detection, Screening, and Local/Regional Therapy

Track

Local/Regional Therapy,Systemic Therapy,Risk Assessment, Prevention, Early Detection, and Screening

Sub Track

Biology in Local/Regional Management

Citation

J Clin Oncol 33, 2015 (suppl 28S; abstr 37)

DOI

10.1200/jco.2015.33.28_suppl.37

Abstract #

37

Poster Bd #

F7

Abstract Disclosures

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