Safety and tolerability of increasing doses of CB-839, a first-in-class, orally administered small molecule inhibitor of glutaminase, in solid tumors.

Authors

null

James J. Harding

Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY

James J. Harding , Melinda L. Telli , Pamela N. Munster , Mai H. Le , Christopher Molineaux , Mark K. Bennett , Erik Mittra , Howard A. Burris III, Amy Sanders Clark , Mark Dunphy , Funda Meric-Bernstam , Manish R. Patel , Angela DeMichele , Jeffrey R. Infante

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Poster Details

Meeting

2015 ASCO Annual Meeting

Session Type

Poster Discussion Session

Session Title

Developmental Therapeutics—Clinical Pharmacology and Experimental Therapeutics

Track

Developmental Therapeutics and Translational Research

Sub Track

Cytotoxic and Other Novel Agents

Clinical Trial Registration Number

NCT02071862

Citation

J Clin Oncol 33, 2015 (suppl; abstr 2512)

DOI

10.1200/jco.2015.33.15_suppl.2512

Abstract #

2512

Poster Bd #

228

Abstract Disclosures