Hopital Europeen G. Pompidou, Paris, France
Florian Scotte , Nicolas Martelli , Alexandre Vainchtock , Isabelle Borget
Background: Venous thromboembolic event (VTE) is a common complication for cancer patients, leading to hospitalizations that increase the burden of cancer management. Our study aimed to estimate the incidence and costs of hospitalizations for VTE, in French patients with breast cancer (BC), colon cancer (CC), lung cancer (LC) or prostate cancer (PC), four of the most frequent cancers in France. Methods: We used the French national hospital database (PMSI) to select new patients with BC, CC, LC or PC in 2010, who had at least one VTE-related hospitalization during the following two years. VTE-related stays and patients were identified using the disease-specific ICD-10 codes. Hospital costs were calculated over stays with VTE considered as primary/related diagnosis. Costs were estimated from the healthcare system perspective, using the French official tariffs. Results: Among 194,964 patients newly diagnosed in 2010 with BC, CC, LC or PC in 2010, 8,909 (4.6%) were hospitalized for a VTE or experienced a VTE at hospital, representing 12,880 hospital stays. During the two-year follow-up, 2,053 (23.0%) patients were re-hospitalized for a VTE recurrence, representing 3,969 stays (30.8% of admissions for VTE). For one patient with VTE who did not experience recurrence, the mean hospital cost over two years ranged from €3,302 to €3,674. This amount was increased in patients with recurrent VTE, as it ranged from €5,441 to €5,692 per patient. Hospitalizations for VTE associated with those 4 types of cancer only were responsible for an overall expenditure reaching €13.30 millions over two years, including €1.82 millions due to recurrent events. Conclusions: In cancer patients, VTE-related hospitalizations remain frequent and induce a notable cost. Prevention and management in respect to guidelines would be an efficient way to reduce the incidence of this complication and moderate its economic cost.
Mean cost / patient without recurrence | Mean cost / patient with recurrence | Total cost | |
---|---|---|---|
Breast cancer | €3,302 | €5,545 | €1,976,235 |
Colon cancer | €3,612 | €5,441 | € 3,985,719 |
Lung cancer | €3,674 | €5,676 | € 5,902,041 |
Prostate cancer | €3,611 | €5,692 | €1,426,356 |
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Abstract Disclosures
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First Author: Isabelle Borget
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First Author: Florian Scotte