GAIN-(C): Efficacy and safety analysis of imgatuzumab (GA201), a novel dual-acting monoclonal antibody (mAb) designed to enhance antibody-dependent cellular cytotoxicity (ADCC), in combination with FOLFIRI compared to cetuximab plus FOLFIRI in second-line KRAS exon 2 wild type (e2WT) or with FOLFIRI alone in mutated (e2MT) metastatic colorectal cancer (mCRC).

Authors

null

John A. Bridgewater

UCL Cancer Institute, University College London, London, United Kingdom

John A. Bridgewater , Andres Cervantes , Ben Markman , Salvatore Siena , Antonio Cubillo , Rocio Garcia Carbonero , Darren Sigal , Giuseppe Aprile , David Cunningham , Cristina Nadal , Carles Pericay , Leslie M. Samuel , Daniel Hochhauser , Jose Alejandro Perez-Fidalgo , Andrew Strickland , Cecile Guizani , Sophie Golding , Vanesa Lopez Valverde , Marion Gabriele Ott , Josep Tabernero

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Poster Details

Meeting

2015 Gastrointestinal Cancers Symposium

Session Type

Poster Session

Session Title

General Poster Session C: Cancers of the Colon, Rectum, and Anus

Track

Cancers of the Colon, Rectum, and Anus

Sub Track

Multidisciplinary Treatment

Clinical Trial Registration Number

NCT01326000

Citation

J Clin Oncol 33, 2015 (suppl 3; abstr 669)

DOI

10.1200/jco.2015.33.3_suppl.669

Abstract #

669

Poster Bd #

D11

Abstract Disclosures